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Perturbation of Thymocyte Development Underlies the PRRS Pandemic: A Testable Hypothesis
Porcine reproductive and respiratory syndrome virus (PRRSV) causes immune dysregulation during the Critical Window of Immunological Development. We hypothesize that thymocyte development is altered by infected thymic antigen presenting cells (TAPCs) in the fetal/neonatal thymus that interact with do...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529568/ https://www.ncbi.nlm.nih.gov/pubmed/31156633 http://dx.doi.org/10.3389/fimmu.2019.01077 |