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TREML2 Mutation Mediate Alzheimer’s Disease Risk by Altering Neuronal Degeneration

A coding missense mutation (rs3747742) in triggering receptor expressed on myeloid cell-like 2 (TREML2) has been recently proposed as an important protective factor against Alzheimer’s disease (AD). However, the link between TREML2 and AD pathology remains unclear. Therefore, we explored the associa...

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Detalles Bibliográficos
Autores principales: Song, Ya-Nan, Li, Jie-Qiong, Tan, Chen-Chen, Wang, Hui-Fu, Tan, Meng-Shan, Cao, Xi-Peng, Yu, Jin-Tai, Tan, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529571/
https://www.ncbi.nlm.nih.gov/pubmed/31156362
http://dx.doi.org/10.3389/fnins.2019.00455