Curcumin reverses oxaliplatin resistance in human colorectal cancer via regulation of TGF-β/Smad2/3 signaling pathway

Background: Oxaliplatin (OXA) resistance is a main obstacle to the chemotherapy of colorectal cancer (CRC). Epithelial-mesenchymal transition (EMT), which is mainly regulated by TGF-β/Smad signaling pathway, has gradually been recognized as an important mechanism for tumor chemoresistance. Studies h...

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Detalles Bibliográficos
Autores principales: Yin, Jiahuan, Wang, Li, Wang, Yong, Shen, Hailong, Wang, Xiaojie, Wu, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529728/
https://www.ncbi.nlm.nih.gov/pubmed/31190888
http://dx.doi.org/10.2147/OTT.S199601

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529728/
https://www.ncbi.nlm.nih.gov/pubmed/31190888
http://dx.doi.org/10.2147/OTT.S199601

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