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Irradiation increases the immunogenicity of lung cancer cells and irradiation-based tumor cell vaccine elicits tumor-specific T cell responses in vivo

Background: During the past decades, great efforts have been built to develop lung cancer vaccines. Whole tumor cell lysate (TCL) are ideal sources of antigens for cancer vaccine design, which however have limited efficacy due to insufficient immunogenicity. Recently, radiotherapy has been closely r...

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Detalles Bibliográficos
Autores principales: Luo, Lumeng, Lv, Minghe, Zhuang, Xibing, Zhang, Qi, Qiao, Tiankui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529730/
https://www.ncbi.nlm.nih.gov/pubmed/31190880
http://dx.doi.org/10.2147/OTT.S197516