Aminoglycoside Enhances the Delivery of Antisense Morpholino Oligonucleotides In Vitro and in mdx Mice

Antisense oligonucleotide (AO) therapy has been the specific treatment for Duchenne muscular dystrophy, with ongoing clinical trials. However, therapeutic applications of AOs remain limited, particularly because of the lack of efficient cellular delivery methods imperative for achieving efficacy. In...

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Detalles Bibliográficos
Autores principales: Wang, Mingxing, Wu, Bo, Shah, Sapana N., Lu, Peijuan, Lu, Qilong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529765/
https://www.ncbi.nlm.nih.gov/pubmed/31121478
http://dx.doi.org/10.1016/j.omtn.2019.04.023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529765/
https://www.ncbi.nlm.nih.gov/pubmed/31121478
http://dx.doi.org/10.1016/j.omtn.2019.04.023

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