A Bioluminescence Resonance Energy Transfer-Based Approach for Determining Antibody-Receptor Occupancy In Vivo

Elucidating receptor occupancy (RO) of monoclonal antibodies (mAbs) is a crucial step in characterizing the therapeutic efficacy of mAbs. However, the in vivo assessment of RO, particularly within peripheral tissues, is greatly limited by current technologies. In the present study, we developed a bi...

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Detalles Bibliográficos
Autores principales: Tang, Yu, Parag-Sharma, Kshitij, Amelio, Antonio L., Cao, Yanguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529791/
https://www.ncbi.nlm.nih.gov/pubmed/31121469
http://dx.doi.org/10.1016/j.isci.2019.05.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529791/
https://www.ncbi.nlm.nih.gov/pubmed/31121469
http://dx.doi.org/10.1016/j.isci.2019.05.003

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