Rewiring the Epigenetic Networks in MLL-Rearranged Leukemias: Epigenetic Dysregulation and Pharmacological Interventions

Leukemias driven by chromosomal translocation of the mixed-lineage leukemia gene (MLL or KMT2A) are highly prevalent in pediatric oncology. The poor survival rate and lack of an effective targeted therapy for patients with MLL-rearranged (MLL-r) leukemias emphasize an urgent need for improved knowle...

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Detalles Bibliográficos
Autores principales: Chan, Anthony K. N., Chen, Chun-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529847/
https://www.ncbi.nlm.nih.gov/pubmed/31157223
http://dx.doi.org/10.3389/fcell.2019.00081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529847/
https://www.ncbi.nlm.nih.gov/pubmed/31157223
http://dx.doi.org/10.3389/fcell.2019.00081

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