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Alkaline Ceramidase Mediates the Oxidative Stress Response in Drosophila melanogaster Through Sphingosine

Alkaline ceramidase (Dacer) in Drosophila melanogaster was demonstrated to be resistant to paraquat-induced oxidative stress. However, the underlying mechanism for this resistance remained unclear. Here, we showed that sphingosine feeding triggered the accumulation of hydrogen peroxide (H(2)O(2)). D...

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Detalles Bibliográficos
Autores principales: Zhang, Chun-Hong, Zhang, Min-Jing, Shi, Xiao-Xiao, Mao, Cungui, Zhu, Zeng-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529914/
https://www.ncbi.nlm.nih.gov/pubmed/31115476
http://dx.doi.org/10.1093/jisesa/iez042