IRF1 Maintains Optimal Constitutive Expression of Antiviral Genes and Regulates the Early Antiviral Response

Viral defense at mucosal sites depends on interferons (IFN) and IFN stimulated genes (ISGs), either of which may be constitutively expressed to maintain an “antiviral state” (AVS). However, the mechanisms that govern the AVS are poorly defined. Using a BEAS-2B respiratory epithelial cell line defici...

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Detalles Bibliográficos
Autores principales: Panda, Debasis, Gjinaj, Erisa, Bachu, Mahesh, Squire, Erica, Novatt, Hilary, Ozato, Keiko, Rabin, Ronald L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529937/
https://www.ncbi.nlm.nih.gov/pubmed/31156620
http://dx.doi.org/10.3389/fimmu.2019.01019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529937/
https://www.ncbi.nlm.nih.gov/pubmed/31156620
http://dx.doi.org/10.3389/fimmu.2019.01019

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