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IRF1 Maintains Optimal Constitutive Expression of Antiviral Genes and Regulates the Early Antiviral Response
Viral defense at mucosal sites depends on interferons (IFN) and IFN stimulated genes (ISGs), either of which may be constitutively expressed to maintain an “antiviral state” (AVS). However, the mechanisms that govern the AVS are poorly defined. Using a BEAS-2B respiratory epithelial cell line defici...
Autores principales: | Panda, Debasis, Gjinaj, Erisa, Bachu, Mahesh, Squire, Erica, Novatt, Hilary, Ozato, Keiko, Rabin, Ronald L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529937/ https://www.ncbi.nlm.nih.gov/pubmed/31156620 http://dx.doi.org/10.3389/fimmu.2019.01019 |
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