Rack1 mediates tyrosine phosphorylation of Anxa2 by Src and promotes invasion and metastasis in drug-resistant breast cancer cells

BACKGROUND: Acquirement of resistance is always associated with a highly aggressive phenotype of tumor cells. Recent studies have revealed that Annexin A2 (Anxa2) is a key protein that links drug resistance and cancer metastasis. A high level of Anxa2 in cancer tissues is correlated to a highly aggr...

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Detalles Bibliográficos
Autores principales: Fan, Yanling, Si, Weiyao, Ji, Wei, Wang, Zhiyong, Gao, Zicong, Tian, Ran, Song, Weijie, Zhang, He, Niu, Ruifang, Zhang, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530024/
https://www.ncbi.nlm.nih.gov/pubmed/31113450
http://dx.doi.org/10.1186/s13058-019-1147-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530024/
https://www.ncbi.nlm.nih.gov/pubmed/31113450
http://dx.doi.org/10.1186/s13058-019-1147-7

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