Cargando…

Reduced eIF3d accelerates HIV disease progression by attenuating CD8+ T cell function

BACKGROUND: In human immunodeficiency virus (HIV) infection, 10–15% of individuals exhibit a rapid decline in CD4+ T cells and become rapid progressors (RPs). Overall, understanding the factors affecting rapid disease progression in early HIV infection (EHI) can aid in treatment initiation. Recent s...

Descripción completa

Detalles Bibliográficos
Autores principales: Pan, Ying, Zhang, Zi-Ning, Yin, Lin-Bo, Fu, Ya-Jing, Jiang, Yong-Jun, Shang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530059/
https://www.ncbi.nlm.nih.gov/pubmed/31118081
http://dx.doi.org/10.1186/s12967-019-1925-0