Tobacco exposure inhibits SPLUNC1-dependent antimicrobial activity

BACKGROUND: Tobacco smoke exposure impairs the lung’s innate immune response, leading to an increased risk of chronic infections. SPLUNC1 is a secreted, multifunctional innate defense protein that has antimicrobial activity against Gram negative organisms. We hypothesize that tobacco smoke-induced S...

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Detalles Bibliográficos
Autores principales: Moore, Patrick J., Sesma, Juliana, Alexis, Neil E., Tarran, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530064/
https://www.ncbi.nlm.nih.gov/pubmed/31113421
http://dx.doi.org/10.1186/s12931-019-1066-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530064/
https://www.ncbi.nlm.nih.gov/pubmed/31113421
http://dx.doi.org/10.1186/s12931-019-1066-2

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