N-n-Butyl Haloperidol Iodide Ameliorates Oxidative Stress in Mitochondria Induced by Hypoxia/Reoxygenation through the Mitochondrial c-Jun N-Terminal Kinase/Sab/Src/Reactive Oxygen Species Pathway in H9c2 Cells

Both c-Jun N-terminal kinase (JNK) and reactive oxygen species (ROS) play important roles in myocardial ischemia/reperfusion (I/R) injury. Our previous studies suggest that N-n-butyl haloperidol iodide (F(2)) exerts cardioprotection by reducing ROS production and JNK activation caused by I/R. In thi...

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Detalles Bibliográficos
Autores principales: Chu, Qianwen, Zhang, Yanmei, Zhong, Shuping, Gao, Fenfei, Chen, Yicun, Wang, Bin, Zhang, Zhaojing, Cai, Wenfeng, Li, Weiqiu, Zheng, Fuchun, Shi, Ganggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530120/
https://www.ncbi.nlm.nih.gov/pubmed/31205589
http://dx.doi.org/10.1155/2019/7417561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530120/
https://www.ncbi.nlm.nih.gov/pubmed/31205589
http://dx.doi.org/10.1155/2019/7417561

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