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Age-Dependent Oxidative Stress Elevates Arginase 1 and Uncoupled Nitric Oxide Synthesis in Skeletal Muscle of Aged Mice

Aging is associated with reduced muscle mass (sarcopenia) and poor bone quality (osteoporosis), which together increase the incidence of falls and bone fractures. It is widely appreciated that aging triggers systemic oxidative stress, which can impair myoblast cell survival and differentiation. We p...

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Detalles Bibliográficos
Autores principales: Pandya, Chirayu D., Lee, Byung, Toque, Haroldo A., Mendhe, Bharati, Bragg, Robert T., Pandya, Bhaumik, Atawia, Reem T., Isales, Carlos, Hamrick, Mark, Caldwell, R. William, Fulzele, Sadanand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530149/
https://www.ncbi.nlm.nih.gov/pubmed/31205583
http://dx.doi.org/10.1155/2019/1704650