Cargando…
Age-Dependent Oxidative Stress Elevates Arginase 1 and Uncoupled Nitric Oxide Synthesis in Skeletal Muscle of Aged Mice
Aging is associated with reduced muscle mass (sarcopenia) and poor bone quality (osteoporosis), which together increase the incidence of falls and bone fractures. It is widely appreciated that aging triggers systemic oxidative stress, which can impair myoblast cell survival and differentiation. We p...
Autores principales: | Pandya, Chirayu D., Lee, Byung, Toque, Haroldo A., Mendhe, Bharati, Bragg, Robert T., Pandya, Bhaumik, Atawia, Reem T., Isales, Carlos, Hamrick, Mark, Caldwell, R. William, Fulzele, Sadanand |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530149/ https://www.ncbi.nlm.nih.gov/pubmed/31205583 http://dx.doi.org/10.1155/2019/1704650 |
Ejemplares similares
-
Kynurenine, a Tryptophan Metabolite That Increases with Age, Induces Muscle Atrophy and Lipid Peroxidation
por: Kaiser, Helen, et al.
Publicado: (2019) -
Depletion of the miR-34a “sponge” MALAT1 in aging skeletal muscle: Implications for age-related muscle loss
por: Ruan, Ling, et al.
Publicado: (2021) -
Muscle-derived miR-34a increases with age in circulating extracellular vesicles and induces senescence of bone marrow stem cells
por: Fulzele, Sadanand, et al.
Publicado: (2019) -
Inhibiting MicroRNA-141-3p Improves Musculoskeletal Health in Aged Mice
por: Vyavahare, Sagar, et al.
Publicado: (2023) -
Long Non-coding RNA MALAT1 Is Depleted With Age in Skeletal Muscle in vivo and MALAT1 Silencing Increases Expression of TGF-β1 in vitro
por: Ruan, Ling, et al.
Publicado: (2022)