Hemagglutinin-neuraminidase and fusion proteins of virulent Newcastle disease virus cooperatively disturb fusion–fission homeostasis to enhance mitochondrial function by activating the unfolded protein response of endoplasmic reticulum and mitochondrial stress

The fusogenically activated F and HN proteins of virulent NDV induce complete autophagic flux in DF-1 and A549 cells. However, the effect of both glycoproteins on mitochondria remains elusive. Here, we found that F and HN cooperation increases mitochondrial biogenesis but does not cause the mitochon...

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Detalles Bibliográficos
Autores principales: Ren, Shanhui, Rehman, Zaib Ur, Shi, Mengyu, Yang, Bin, Liu, Panrao, Yin, Yuncong, Qu, Yurong, Meng, Chunchun, Yang, Zengqi, Gao, Xiaolong, Sun, Yingjie, Ding, Chan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530190/
https://www.ncbi.nlm.nih.gov/pubmed/31118100
http://dx.doi.org/10.1186/s13567-019-0654-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530190/
https://www.ncbi.nlm.nih.gov/pubmed/31118100
http://dx.doi.org/10.1186/s13567-019-0654-y

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