Monitoring flux in signalling pathways through measurements of 4EBP1-mediated eIF4F complex assembly

BACKGROUND: The most commonly occurring cancer mutations, including oncogenes such as MYC, Ras and PIK3C, are found in signal transductions pathways feeding into the translational machinery. A broad range of translation initiation factors are also commonly found to be either amplified or mis-regulat...

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Detalles Bibliográficos
Autores principales: Frosi, Yuri, Usher, Rachael, Lian, Dawn Thean Gek, Lane, David P., Brown, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530213/
https://www.ncbi.nlm.nih.gov/pubmed/31118010
http://dx.doi.org/10.1186/s12915-019-0658-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530213/
https://www.ncbi.nlm.nih.gov/pubmed/31118010
http://dx.doi.org/10.1186/s12915-019-0658-0

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