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Monitoring flux in signalling pathways through measurements of 4EBP1-mediated eIF4F complex assembly
BACKGROUND: The most commonly occurring cancer mutations, including oncogenes such as MYC, Ras and PIK3C, are found in signal transductions pathways feeding into the translational machinery. A broad range of translation initiation factors are also commonly found to be either amplified or mis-regulat...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530213/ https://www.ncbi.nlm.nih.gov/pubmed/31118010 http://dx.doi.org/10.1186/s12915-019-0658-0 |