Continuous Readout versus Titer-Based Assays of Influenza Vaccine Trials: Sensitivity, Specificity, and False Discovery Rates

The current gold standard for measuring antibody-based immunity to influenza viruses relies on the hemagglutinin inhibition assay (HAI), an 80-year-old technology, and the microneutralization assay (MN). Both assays use serial dilution to provide a discrete, ranked readout of 8–14 categorical titer...

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Detalles Bibliográficos
Autores principales: Li, Dongmei, Wang, Jiong, Garigen, Jessica, Treanor, John J., Zand, Martin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530215/
https://www.ncbi.nlm.nih.gov/pubmed/31205481
http://dx.doi.org/10.1155/2019/9287120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530215/
https://www.ncbi.nlm.nih.gov/pubmed/31205481
http://dx.doi.org/10.1155/2019/9287120

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