Trans-Cinnamaldehyde Inhibits IL-1β-Stimulated Inflammation in Chondrocytes by Suppressing NF-κB and p38-JNK Pathways and Exerts Chondrocyte Protective Effects in a Rat Model of Osteoarthritis

OBJECTIVE: Trans-cinnamaldehyde (TCA), a compound from Cinnamomum cassia Presl, has been reported to have anti-inflammatory effect. However, its effect on cartilage degradation in osteoarthritis is unclear. This study is designed to examine the effects of TCA on cartilage in vitro and in vivo. MATER...

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Detalles Bibliográficos
Autores principales: Xia, Tianwei, Gao, Runzi, Zhou, Guowei, Liu, Jinzhu, Li, Jinsheng, Shen, Jirong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530235/
https://www.ncbi.nlm.nih.gov/pubmed/31205941
http://dx.doi.org/10.1155/2019/4039472

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530235/
https://www.ncbi.nlm.nih.gov/pubmed/31205941
http://dx.doi.org/10.1155/2019/4039472

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