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Trans-Cinnamaldehyde Inhibits IL-1β-Stimulated Inflammation in Chondrocytes by Suppressing NF-κB and p38-JNK Pathways and Exerts Chondrocyte Protective Effects in a Rat Model of Osteoarthritis
OBJECTIVE: Trans-cinnamaldehyde (TCA), a compound from Cinnamomum cassia Presl, has been reported to have anti-inflammatory effect. However, its effect on cartilage degradation in osteoarthritis is unclear. This study is designed to examine the effects of TCA on cartilage in vitro and in vivo. MATER...
Autores principales: | Xia, Tianwei, Gao, Runzi, Zhou, Guowei, Liu, Jinzhu, Li, Jinsheng, Shen, Jirong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530235/ https://www.ncbi.nlm.nih.gov/pubmed/31205941 http://dx.doi.org/10.1155/2019/4039472 |
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