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Exploring the Immunological Mechanisms Underlying the Anti-vascular Endothelial Growth Factor Activity in Tumors

Several studies report the key role of the vascular endothelial growth factor (VEGF) signaling on angiogenesis and on tumor growth. This has led to the development of a number of VEGF-targeted agents to treat cancer patients by disrupting the tumor blood vessel supply. Of them, bevacizumab, an FDA-a...

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Detalles Bibliográficos
Autores principales: de Aguiar, Rodrigo Barbosa, de Moraes, Jane Zveiter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530399/
https://www.ncbi.nlm.nih.gov/pubmed/31156623
http://dx.doi.org/10.3389/fimmu.2019.01023