Actin Dynamics, Regulated by RhoA-LIMK-Cofilin Signaling, Mediates Rod Photoreceptor Axonal Retraction After Retinal Injury

PURPOSE: Retraction of the axon terminals of rod photoreceptors after retinal detachment breaks the first synapse in the visual pathway, resulting in visual impairment. Previous work showed that the mechanism of axonal retraction involves RhoA signaling and its downstream effector LIM Kinase (LIMK)...

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Detalles Bibliográficos
Autores principales: Wang, Weiwei, Halasz, Eva, Townes-Anderson, Ellen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2019
Materias:
Retina
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530517/
https://www.ncbi.nlm.nih.gov/pubmed/31112612
http://dx.doi.org/10.1167/iovs.18-26077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530517/
https://www.ncbi.nlm.nih.gov/pubmed/31112612
http://dx.doi.org/10.1167/iovs.18-26077

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