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A sulfonium tethered peptide ligand rapidly and selectively modifies protein cysteine in vicinity
Significant efforts have been invested to develop site-specific protein modification methodologies in the past two decades. In most cases, a reactive moiety was installed onto ligands with the sole purpose of reacting with specific residues in proteins. Herein, we report a unique peptide macrocycliz...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530539/ https://www.ncbi.nlm.nih.gov/pubmed/31183045 http://dx.doi.org/10.1039/c9sc00034h |