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A sulfonium tethered peptide ligand rapidly and selectively modifies protein cysteine in vicinity

Significant efforts have been invested to develop site-specific protein modification methodologies in the past two decades. In most cases, a reactive moiety was installed onto ligands with the sole purpose of reacting with specific residues in proteins. Herein, we report a unique peptide macrocycliz...

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Detalles Bibliográficos
Autores principales: Wang, Dongyuan, Yu, Mengying, Liu, Na, Lian, Chenshan, Hou, Zhanfeng, Wang, Rui, Zhao, Rongtong, Li, Wenjun, Jiang, Yixiang, Shi, Xiaodong, Li, Shuiming, Yin, Feng, Li, Zigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530539/
https://www.ncbi.nlm.nih.gov/pubmed/31183045
http://dx.doi.org/10.1039/c9sc00034h