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On the problem of confounders in modeling gene expression

MOTIVATION: Modeling of Transcription Factor (TF) binding from both ChIP-seq and chromatin accessibility data has become prevalent in computational biology. Several models have been proposed to generate new hypotheses on transcriptional regulation. However, there is no distinct approach to derive TF...

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Detalles Bibliográficos
Autores principales: Schmidt, Florian, Schulz, Marcel H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530814/
https://www.ncbi.nlm.nih.gov/pubmed/30084962
http://dx.doi.org/10.1093/bioinformatics/bty674