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Pathway-specific protein domains are predictive for human diseases

Protein domains are basic functional units of proteins. Many protein domains are pervasive among diverse biological processes, yet some are associated with specific pathways. Human complex diseases are generally viewed as pathway-level disorders. Therefore, we hypothesized that pathway-specific doma...

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Detalles Bibliográficos
Autores principales: Shim, Jung Eun, Kim, Ji Hyun, Shin, Junha, Lee, Ji Eun, Lee, Insuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530867/
https://www.ncbi.nlm.nih.gov/pubmed/31075101
http://dx.doi.org/10.1371/journal.pcbi.1007052