Cargando…
Structure-based inhibitory peptide design targeting peptide-substrate binding site in EGFR tyrosine kinase
EGFR (epidermal growth factor receptor) plays the critical roles in the vital cell activities, proliferation, differentiation, migration and survival in response to polypeptide growth factor ligands. Aberrant activation of this receptor has been demonstrated in many human cancers, particularly in no...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530890/ https://www.ncbi.nlm.nih.gov/pubmed/31116768 http://dx.doi.org/10.1371/journal.pone.0217031 |