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Slc12a8 is a nicotinamide mononucleotide transporter

Nicotinamide mononucleotide (NMN) is a biosynthetic precursor of NAD(+) known to promote cellular NAD(+) production and counteract age-associated pathologies associated with a decline in tissue NAD(+) levels. How NMN is taken up into cells has not been entirely clear. Here we show that the Slc12a8 g...

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Detalles Bibliográficos
Autores principales: Grozio, Alessia, Mills, Kathryn F., Yoshino, Jun, Bruzzone, Santina, Sociali, Giovanna, Tokizane, Kyohei, Lei, Hanyue Cecilia, Cunningham, Richard, Sasaki, Yo, Migaud, Marie E., Imai, Shin-ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530925/
https://www.ncbi.nlm.nih.gov/pubmed/31131364
http://dx.doi.org/10.1038/s42255-018-0009-4