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cAMP metabolism controls caspase-11 inflammasome activation and pyroptosis in sepsis

The ability of cytosolic lipopolysaccharide (LPS) to activate caspase-11–dependent nonclassical inflammasome is intricately controlled to avoid excessive inflammatory responses. However, very little is known about the regulatory role of various metabolic pathways in the control of caspase-11 activat...

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Detalles Bibliográficos
Autores principales: Chen, Ruochan, Zeng, Ling, Zhu, Shan, Liu, Jiao, Zeh, Herbert J., Kroemer, Guido, Wang, Haichao, Billiar, Timothy R., Jiang, Jianxin, Tang, Daolin, Kang, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531004/
https://www.ncbi.nlm.nih.gov/pubmed/31131320
http://dx.doi.org/10.1126/sciadv.aav5562