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cAMP metabolism controls caspase-11 inflammasome activation and pyroptosis in sepsis
The ability of cytosolic lipopolysaccharide (LPS) to activate caspase-11–dependent nonclassical inflammasome is intricately controlled to avoid excessive inflammatory responses. However, very little is known about the regulatory role of various metabolic pathways in the control of caspase-11 activat...
Autores principales: | Chen, Ruochan, Zeng, Ling, Zhu, Shan, Liu, Jiao, Zeh, Herbert J., Kroemer, Guido, Wang, Haichao, Billiar, Timothy R., Jiang, Jianxin, Tang, Daolin, Kang, Rui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531004/ https://www.ncbi.nlm.nih.gov/pubmed/31131320 http://dx.doi.org/10.1126/sciadv.aav5562 |
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