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Dynamics of the EAG1 K(+) channel selectivity filter assessed by molecular dynamics simulations

EAG1 channels belong to the KCNH family of voltage gated potassium channels. They are expressed in several brain regions and increased expression is linked to certain cancer types. Recent cryo-EM structure determination finally revealed the structure of these channels in atomic detail, allowing comp...

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Detalles Bibliográficos
Autores principales: Bernsteiner, Harald, Bründl, Michael, Stary-Weinzinger, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531291/
https://www.ncbi.nlm.nih.gov/pubmed/28109880
http://dx.doi.org/10.1016/j.bbrc.2017.01.064