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Dynamics of the EAG1 K(+) channel selectivity filter assessed by molecular dynamics simulations
EAG1 channels belong to the KCNH family of voltage gated potassium channels. They are expressed in several brain regions and increased expression is linked to certain cancer types. Recent cryo-EM structure determination finally revealed the structure of these channels in atomic detail, allowing comp...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531291/ https://www.ncbi.nlm.nih.gov/pubmed/28109880 http://dx.doi.org/10.1016/j.bbrc.2017.01.064 |