SIRT6, a novel direct transcriptional target of FoxO3a, mediates colon cancer therapy

SIRT6, NAD+-dependent deacetylase sirtuin 6, has recently shown to suppress tumor growth in several types of cancer. Colon cancer is a challenging carcinoma associated with high morbidity and death. However, whether SIRT6 play a direct role in colon tumorigenesis and the underlying mechanism are not...

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Detalles Bibliográficos
Autores principales: Zhang, Yingjie, Nie, Liming, Xu, Keqian, Fu, Yang, Zhong, Juchang, Gu, Kongzhen, Zhang, Lingling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531295/
https://www.ncbi.nlm.nih.gov/pubmed/31149050
http://dx.doi.org/10.7150/thno.29724

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531295/
https://www.ncbi.nlm.nih.gov/pubmed/31149050
http://dx.doi.org/10.7150/thno.29724

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