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Biodistribution of gadolinium- and near infrared-labeled human umbilical cord mesenchymal stromal cell-derived exosomes in tumor bearing mice

We speculate that exosomes derived from human umbilical cord mesenchymal stromal cells (HUC-MSCs) will accumulate within tumors and have the potential for both tumor location or drug delivery. Methods: To determine proof of concept, HUC-MSC exosomes were labeled with an MRI contrast agent, gadoliniu...

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Detalles Bibliográficos
Autores principales: Abello, Javier, Nguyen, Tuyen Duong Thanh, Marasini, Ramesh, Aryal, Santosh, Weiss, Mark Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531310/
https://www.ncbi.nlm.nih.gov/pubmed/31149047
http://dx.doi.org/10.7150/thno.30030