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Injectable polypeptide hydrogel-based co-delivery of vaccine and immune checkpoint inhibitors improves tumor immunotherapy

Immunotherapy, an attractive option for cancer treatment, necessitates the direct stimulation of immune cells in vivo and the simultaneous effective inhibition of immunosuppressive tumor microenvironments. Methods: In the present study, we developed an injectable PEG-b-poly(L-alanine) hydrogel for c...

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Detalles Bibliográficos
Autores principales: Song, Huijuan, Yang, Pengxiang, Huang, Pingsheng, Zhang, Chuangnian, Kong, Deling, Wang, Weiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531311/
https://www.ncbi.nlm.nih.gov/pubmed/31149045
http://dx.doi.org/10.7150/thno.30577