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Toll-like receptors TLR2 and TLR4 block the replication of pancreatic β cells in diet-induced obesity
Consumption of high energy Western diet triggers mild adaptive β cell proliferation to compensate for peripheral insulin resistance; however, the underlying molecular mechanism remains unclear. Here we show that the Toll-like receptors TLR2 and TLR4 inhibited the diet-induced replication of β cells...
Autores principales: | , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531334/ https://www.ncbi.nlm.nih.gov/pubmed/31110312 http://dx.doi.org/10.1038/s41590-019-0396-z |