Toll-like receptors TLR2 and TLR4 block the replication of pancreatic β cells in diet-induced obesity

Consumption of high energy Western diet triggers mild adaptive β cell proliferation to compensate for peripheral insulin resistance; however, the underlying molecular mechanism remains unclear. Here we show that the Toll-like receptors TLR2 and TLR4 inhibited the diet-induced replication of β cells...

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Detalles Bibliográficos
Autores principales: Ji, Yewei, Sun, Shengyi, Shrestha, Neha, Darragh, Laurel B., Shirakawa, Jun, Xing, Yuan, He, Yi, Carboneau, Bethany A., Kim, Hana, An, Duo, Ma, Minglin, Oberhozler, Jose, Soleimanpour, Scott A., Gannon, Maureen, Liu, Chengyang, Naji, Ali, Kulkarni, Rohit N., Wang, Yong, Kersten, Sander, Qi, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531334/
https://www.ncbi.nlm.nih.gov/pubmed/31110312
http://dx.doi.org/10.1038/s41590-019-0396-z

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