Rapid microarray-based assay for detection of pyrazinamide resistant Mycobacterium tuberculosis

Pyrazinamide (PZA) is a key antibiotic for the treatment of drug susceptible tuberculosis. PZA-resistance is mainly mediated by mutations in the pncA gene; however the current gold standard is a phenotypic drug susceptibility test requiring a well-adjusted pH-value for reliable results. Our melting...

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Detalles Bibliográficos
Autores principales: Havlicek, Juliane, Dachsel, Beatrice, Slickers, Peter, Andres, Sönke, Beckert, Patrick, Feuerriegel, Silke, Niemann, Stefan, Merker, Matthias, Labugger, Ines
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Biomedical 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531379/
https://www.ncbi.nlm.nih.gov/pubmed/30733004
http://dx.doi.org/10.1016/j.diagmicrobio.2018.12.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531379/
https://www.ncbi.nlm.nih.gov/pubmed/30733004
http://dx.doi.org/10.1016/j.diagmicrobio.2018.12.011

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