Anchoring cortical granules in the cortex ensures trafficking to the plasma membrane for post-fertilization exocytosis

Following fertilization, cortical granules exocytose ovastacin, a metalloendopeptidase that cleaves ZP2 in the zona pellucida surrounding mouse eggs to prevent additional sperm binding. Using high- and super-resolution imaging with ovastacin(mCherry) as a fluorescent marker, we characterize cortical...

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Detalles Bibliográficos
Autores principales: Vogt, Edgar-John, Tokuhiro, Keizo, Guo, Min, Dale, Ryan, Yang, Guanghui, Shin, Seung-Wook, Movilla, Maria Jimenez, Shroff, Hari, Dean, Jurrien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531442/
https://www.ncbi.nlm.nih.gov/pubmed/31118423
http://dx.doi.org/10.1038/s41467-019-10171-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531442/
https://www.ncbi.nlm.nih.gov/pubmed/31118423
http://dx.doi.org/10.1038/s41467-019-10171-7

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