Interaction of SNARE Mimetic Peptides with Lipid bilayers: Effects of Secondary Structure, Bilayer Composition and Lipid Anchoring

The coiled-coil forming peptides ‘K’ enriched in lysine and ‘E’ enriched in glutamic acid have been used as a minimal SNARE mimetic system for membrane fusion. Here we describe atomistic molecular dynamics simulations to characterize the interactions of these peptides with lipid bilayers for two dif...

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Detalles Bibliográficos
Autores principales: Wagle, Swapnil, Georgiev, Vasil N., Robinson, Tom, Dimova, Rumiana, Lipowsky, Reinhard, Grafmüller, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531448/
https://www.ncbi.nlm.nih.gov/pubmed/31118479
http://dx.doi.org/10.1038/s41598-019-43418-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531448/
https://www.ncbi.nlm.nih.gov/pubmed/31118479
http://dx.doi.org/10.1038/s41598-019-43418-w

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