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Interaction of SNARE Mimetic Peptides with Lipid bilayers: Effects of Secondary Structure, Bilayer Composition and Lipid Anchoring
The coiled-coil forming peptides ‘K’ enriched in lysine and ‘E’ enriched in glutamic acid have been used as a minimal SNARE mimetic system for membrane fusion. Here we describe atomistic molecular dynamics simulations to characterize the interactions of these peptides with lipid bilayers for two dif...
Autores principales: | Wagle, Swapnil, Georgiev, Vasil N., Robinson, Tom, Dimova, Rumiana, Lipowsky, Reinhard, Grafmüller, Andrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531448/ https://www.ncbi.nlm.nih.gov/pubmed/31118479 http://dx.doi.org/10.1038/s41598-019-43418-w |
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