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iSuRe-Cre is a genetic tool to reliably induce and report Cre-dependent genetic modifications
Most biomedical research aimed at understanding gene function uses the Cre-Lox system, which consists of the Cre recombinase-dependent deletion of genes containing LoxP sites. This system enables conditional genetic modifications because the expression and activity of the recombinase Cre/CreERT2 can...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531465/ https://www.ncbi.nlm.nih.gov/pubmed/31118412 http://dx.doi.org/10.1038/s41467-019-10239-4 |