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iSuRe-Cre is a genetic tool to reliably induce and report Cre-dependent genetic modifications

Most biomedical research aimed at understanding gene function uses the Cre-Lox system, which consists of the Cre recombinase-dependent deletion of genes containing LoxP sites. This system enables conditional genetic modifications because the expression and activity of the recombinase Cre/CreERT2 can...

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Detalles Bibliográficos
Autores principales: Fernández-Chacón, Macarena, Casquero-García, Verónica, Luo, Wen, Francesca Lunella, Federica, Ferreira Rocha, Susana, Del Olmo-Cabrera, Sergio, Benedito, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531465/
https://www.ncbi.nlm.nih.gov/pubmed/31118412
http://dx.doi.org/10.1038/s41467-019-10239-4