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Combinatorial recognition of clustered RNA elements by the multidomain RNA-binding protein IMP3

How multidomain RNA-binding proteins recognize their specific target sequences, based on a combinatorial code, represents a fundamental unsolved question and has not been studied systematically so far. Here we focus on a prototypical multidomain RNA-binding protein, IMP3 (also called IGF2BP3), which...

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Detalles Bibliográficos
Autores principales: Schneider, Tim, Hung, Lee-Hsueh, Aziz, Masood, Wilmen, Anna, Thaum, Stephanie, Wagner, Jacqueline, Janowski, Robert, Müller, Simon, Schreiner, Silke, Friedhoff, Peter, Hüttelmaier, Stefan, Niessing, Dierk, Sattler, Michael, Schlundt, Andreas, Bindereif, Albrecht
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531468/
https://www.ncbi.nlm.nih.gov/pubmed/31118463
http://dx.doi.org/10.1038/s41467-019-09769-8