Recapitulation of HDV infection in a fully permissive hepatoma cell line allows efficient drug evaluation

Hepatitis delta virus (HDV) depends on the helper function of hepatitis B virus (HBV), which provides the envelope proteins for progeny virus secretion. Current infection-competent cell culture models do not support assembly and secretion of HDV. By stably transducing HepG2 cells with genes encoding...

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Detalles Bibliográficos
Autores principales: Lempp, Florian A., Schlund, Franziska, Rieble, Lisa, Nussbaum, Lea, Link, Corinna, Zhang, Zhenfeng, Ni, Yi, Urban, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531471/
https://www.ncbi.nlm.nih.gov/pubmed/31118422
http://dx.doi.org/10.1038/s41467-019-10211-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531471/
https://www.ncbi.nlm.nih.gov/pubmed/31118422
http://dx.doi.org/10.1038/s41467-019-10211-2

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