Cargando…

Recapitulation of HDV infection in a fully permissive hepatoma cell line allows efficient drug evaluation

Hepatitis delta virus (HDV) depends on the helper function of hepatitis B virus (HBV), which provides the envelope proteins for progeny virus secretion. Current infection-competent cell culture models do not support assembly and secretion of HDV. By stably transducing HepG2 cells with genes encoding...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lempp, Florian A., Schlund, Franziska, Rieble, Lisa, Nussbaum, Lea, Link, Corinna, Zhang, Zhenfeng, Ni, Yi, Urban, Stephan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531471/ https://www.ncbi.nlm.nih.gov/pubmed/31118422 http://dx.doi.org/10.1038/s41467-019-10211-2

Ejemplares similares

HDV Seroprevalence in HBsAg-Positive Patients in China Occurs in Hotspots and Is Not Associated with HCV Mono-Infection
por: Roggenbach, Imme, et al.
Publicado: (2021)

Permissiveness of human hepatoma cell lines for HCV infection
por: Sainz, Bruno, et al.
Publicado: (2012)

HBV and HDV: New Treatments on the Horizon
por: Zuccaro, Valentina, et al.
Publicado: (2021)

Broad-spectrum activity of bulevirtide against clinical isolates of HDV and recombinant pan-genotypic combinations of HBV/HDV
por: Mateo, Roberto, et al.
Publicado: (2023)

HDV-Like Viruses
por: Pérez-Vargas, Jimena, et al.
Publicado: (2021)

Primary Biliary Acids Inhibit Hepatitis D Virus (HDV) Entry into Human Hepatoma Cells Expressing the Sodium-Taurocholate Cotransporting Polypeptide (NTCP)
por: Veloso Alves Pereira, Isabel, et al.
Publicado: (2015)

Induction of hyperammonia in irradiated hepatoma cells: a recapitulation and possible explanation of the phenomenon
por: van Rijn, J, et al.
Publicado: (2004)

AAV-HDV: An Attractive Platform for the In Vivo Study of HDV Biology and the Mechanism of Disease Pathogenesis (†)
por: Maestro, Sheila, et al.
Publicado: (2021)

Circulation of HDV Genotypes in Brazil: Identification of a Putative Novel HDV-8 Subgenotype
por: Mello, Francisco C. A., et al.
Publicado: (2023)

Permissivity of primary hepatocytes and hepatoma cell lines to support hepatitis C virus infection
por: Wilson, Garrick K., et al.
Publicado: (2015)

Generation and characterization of a stable cell line persistently replicating and secreting the human hepatitis delta virus
por: Ni, Yi, et al.
Publicado: (2019)

Combination of Novel Therapies for HDV
por: Elazar, Menashe, et al.
Publicado: (2022)

A Review of HDV Infection
por: Caviglia, Gian Paolo, et al.
Publicado: (2022)

Variable In Vivo Hepatitis D Virus (HDV) RNA Editing Rates According to the HDV Genotype
por: Dziri, Samira, et al.
Publicado: (2021)

A Rapid Point-of-Care Test for the Serodiagnosis of Hepatitis Delta Virus Infection
por: Lempp, Florian A., et al.
Publicado: (2021)

HDV infection rates in northern Vietnam
por: Binh, Mai Thanh, et al.
Publicado: (2018)

HDV Pathogenesis: Unravelling Ariadne’s Thread
por: Tseligka, Eirini D., et al.
Publicado: (2021)

Performance of Hepatitis Delta Virus (HDV) RNA Testing for the Diagnosis of Active HDV Infection: Systematic Review and Meta-analysis
por: Chen, Sisi, et al.
Publicado: (2023)

Permissivity of Primary Human Hepatocytes and Different Hepatoma Cell Lines to Cell Culture Adapted Hepatitis C Virus
por: Helle, Francois, et al.
Publicado: (2013)

Inhibition of telomerase activity by HDV ribozyme in cancers
por: Lu, Yingying, et al.
Publicado: (2011)

Chances for cure in chronic HBV/HDV coinfection
por: Iliescu, Gabriela, et al.
Publicado: (2014)

Hepatitis Delta Virus: HDV-HBV Interactions
por: Sureau, Camille
Publicado: (2006)

Constraint of Base Pairing on HDV Genome Evolution
por: Nagata, Saki, et al.
Publicado: (2021)

Both interferon alpha and lambda can reduce all intrahepatic HDV infection markers in HBV/HDV infected humanized mice
por: Giersch, Katja, et al.
Publicado: (2017)

Hepatitis Delta Virus: Replication Strategy and Upcoming Therapeutic Options for a Neglected Human Pathogen
por: Lempp, Florian A., et al.
Publicado: (2017)

Correction: Permissivity of Primary Human Hepatocytes and Different Hepatoma Cell Lines to Cell Culture Adapted Hepatitis C Virus
por: Helle, Francois, et al.
Publicado: (2019)

Effects of flanking regions on HDV cotranscriptional folding kinetics
por: Wang, Yanli, et al.
Publicado: (2018)

In Vivo Models of HDV Infection: Is Humanizing NTCP Enough?
por: Giersch, Katja, et al.
Publicado: (2021)

Discontinuation of Passive Immunization Is Safe after Liver Transplantation for Combined HBV/HDV Infection
por: Ossami Saidy, Ramin Raul, et al.
Publicado: (2021)

Epidemiological trends of HBV and HDV coinfection among Viennese HIV+ patients
por: Schmidbauer, Caroline, et al.
Publicado: (2021)

Anti-HDV seroprevalance among patients with previous HBV infection
por: Sahin, Abdurrahman, et al.
Publicado: (2018)

Insight into the Contribution and Disruption of Host Processes during HDV Replication
por: Goodrum, Gabrielle, et al.
Publicado: (2018)

Management of Delta Hepatitis 45 Years after the Discovery of HDV
por: Brillanti, Stefano
Publicado: (2022)

An Occult Hepatitis B-Derived Hepatoma Cell Line Carrying Persistent Nuclear Viral DNA and Permissive for Exogenous Hepatitis B Virus Infection
por: Lin, Chih-Lang, et al.
Publicado: (2013)

Macrophage migration inhibitory factor has a permissive role in concanavalin A-induced cell death of human hepatoma cells through autophagy
por: Lai, Y-C, et al.
Publicado: (2015)

Recapitulation
Publicado: (1866)

Successful treatment of HCV/HBV/HDV-coinfection with pegylated interferon and ribavirin
por: Hartl, Janine, et al.
Publicado: (2012)

RNA binding domain of HDV antigen is homologous to the HMG box of SRY
por: Veretnik, S., et al.
Publicado: (2014)

Hepatitis Delta Virus (HDV) and Delta-Like Agents: Insights Into Their Origin
por: Netter, Hans J., et al.
Publicado: (2021)

Key Factors for “Fishing” NTCP as a Functional Receptor for HBV and HDV
por: Yan, Huan, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_npjcchhtibgi569gkmcv8h9io7