AMPK alleviates high uric acid-induced Na(+)-K(+)-ATPase signaling impairment and cell injury in renal tubules

One of the mechanisms in hyperuricemia (HUA)-induced renal tubular injury is the impairment of Na(+)-K(+)-ATPase (NKA) signaling, which further triggers inflammation, autophagy, and mitochondrial dysfunction and leads to cell injury. Here, we used RNA sequencing to screen the most likely regulators...

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Detalles Bibliográficos
Autores principales: Xiao, Jing, Zhu, Sibo, Guan, Haochen, Zheng, Yuqi, Li, Fengqin, Zhang, Xiaoli, Guo, Hui, Wang, Xiaojun, Ye, Zhibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531502/
https://www.ncbi.nlm.nih.gov/pubmed/31118410
http://dx.doi.org/10.1038/s12276-019-0254-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531502/
https://www.ncbi.nlm.nih.gov/pubmed/31118410
http://dx.doi.org/10.1038/s12276-019-0254-y

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