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The ubiquitin ligase PHR promotes directional regrowth of spinal zebrafish axons

To reconnect with their synaptic targets, severed axons need to regrow robustly and directionally along the pre-lesional trajectory. While mechanisms directing axonal regrowth are poorly understood, several proteins direct developmental axon outgrowth, including the ubiquitin ligase PHR (Mycbp2). In...

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Detalles Bibliográficos
Autores principales: Bremer, Juliane, Marsden, Kurt C., Miller, Adam, Granato, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531543/
https://www.ncbi.nlm.nih.gov/pubmed/31149640
http://dx.doi.org/10.1038/s42003-019-0434-2