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Histidine‐rich glycoprotein augments natural killer cell function by modulating PD‐1 expression via CLEC‐1B
Augmentation of natural killer (NK) cell cytotoxicity is one of the greatest challenges for cancer immunotherapy. Although histidine‐rich glycoprotein (HRG), a 75‐kDa glycoprotein with various immunomodulatory activities, reportedly elicits antitumor immunity, its effect on NK cell cytotoxicity is u...
Autores principales: | Nishimura, Yoshito, Wake, Hidenori, Teshigawara, Kiyoshi, Wang, Dengli, Sakaguchi, Masakiyo, Otsuka, Fumio, Nishibori, Masahiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531599/ https://www.ncbi.nlm.nih.gov/pubmed/31143450 http://dx.doi.org/10.1002/prp2.481 |
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