Discovering metabolic disease gene interactions by correlated effects on cellular morphology

OBJECTIVE: Impaired expansion of peripheral fat contributes to the pathogenesis of insulin resistance and Type 2 Diabetes (T2D). We aimed to identify novel disease–gene interactions during adipocyte differentiation. METHODS: Genes in disease-associated loci for T2D, adiposity and insulin resistance...

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Detalles Bibliográficos
Autores principales: Jiao, Yang, Ahmed, Umer, Sim, M.F. Michelle, Bejar, Andrea, Zhang, Xiaolan, Talukder, M. Mesbah Uddin, Rice, Robert, Flannick, Jason, Podgornaia, Anna I., Reilly, Dermot F., Engreitz, Jesse M., Kost-Alimova, Maria, Hartland, Kate, Mercader, Josep-Maria, Georges, Sara, Wagh, Vilas, Tadin-Strapps, Marija, Doench, John G., Edwardson, J. Michael, Rochford, Justin J., Rosen, Evan D., Majithia, Amit R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531784/
https://www.ncbi.nlm.nih.gov/pubmed/30940487
http://dx.doi.org/10.1016/j.molmet.2019.03.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531784/
https://www.ncbi.nlm.nih.gov/pubmed/30940487
http://dx.doi.org/10.1016/j.molmet.2019.03.001

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